(19)
(11) EP 1 585 543 A1

(12)

(43) Date of publication:
19.10.2005 Bulletin 2005/42

(21) Application number: 04704657.8

(22) Date of filing: 23.01.2004
(51) International Patent Classification (IPC)7: A61K 39/00, C07K 14/47, C12N 5/06, A61P 37/06, A61P 37/08
(86) International application number:
PCT/GB2004/000263
(87) International publication number:
WO 2004/064863 (05.08.2004 Gazette 2004/32)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 23.01.2003 GB 0301519
23.01.2003 GB 0301518
23.01.2003 GB 0301515
23.01.2003 GB 0301513
23.01.2003 GB 0301512
23.01.2003 GB 0301510
23.01.2003 GB 0301521
23.01.2003 GB 0301522
23.01.2003 GB 0301524
23.01.2003 GB 0301526
23.01.2003 GB 0301527
23.01.2003 GB 0301529
04.04.2003 WO PCT/GB03/01525
24.05.2003 GB 0312062
01.08.2003 WO PCT/GB03/03285
03.10.2003 GB 0323130
07.01.2004 WO PCT/GB20/04000046

(71) Applicant: Lorantis Limited
Cambridge CB4 0PE (GB)

(72) Inventors:
  • CHAMPION, Brian Robert
    Cambridge CB4 0PE (GB)
  • RAGNO, Silvia
    Cambridge CB4 0PE (GB)
  • YOUNG, Lesley Lynn
    Cambridge CB4 0PE (GB)

(74) Representative: Mallalieu, Catherine Louise et al
D Young & Co 120 Holborn
London EC1N 2DY
London EC1N 2DY (GB)

   


(54) TREATMENT OF AUTOIMMUNE DISEASES USING AN ACTIVATOR FOR THE NOTCH SIGNALING PATHWAY