(19)

(11)

EP 1 590 340 A1

(12)

(43) Date of publication: 02.11.2005 Bulletin 2005/44 (21) Application number: 04707852.2 (22) Date of filing: 04.02.2004

(51) International Patent Classification (IPC)7: C07D 401/04, A61K 31/506, A61P 35/00 (86) International application number: PCT/CA2004/000139 (87) International publication number: WO 2004/069823 (19.08.2004 Gazette 2004/34)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 04.02.2003 US 358556 (71) Applicant: Methylgene, Inc. Saint-Laurent,Quebec H4S 2A1 (CA)	(72) Inventors: DELORME, Daniel St-Lazare, Québec J7T 2B2 (CA) ZHOU, Zhihong Kirkland, Québec J7T 2B2 (CA) (74) Representative: Luderschmidt, Schüler & Partner GbR  Patentanwälte, John-F.-Kennedy-Strasse 4 65189 Wiesbaden 65189 Wiesbaden (DE)