(19)

(11)

EP 1 592 432 A2

(12)

(88) Date of publication A3: 09.09.2005 (43) Date of publication: 09.11.2005 Bulletin 2005/45 (21) Application number: 04702115.9 (22) Date of filing: 14.01.2004

(51) International Patent Classification (IPC)7: A61K 31/715, C08B 37/00 (86) International application number: PCT/US2004/000747 (87) International publication number: WO 2004/064777 (05.08.2004 Gazette 2004/32)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 16.01.2003 US 440496 P (71) Applicant: Pro-Pharmaceuticals, Inc. Newton, MA 02459 (US)	(72) Inventor: PLATT, David Newton, Massachusetts 02459 (US) (74) Representative: Jennings, Tara Romaine et al F. R. Kelly & Co. 27 Clyde Road Ballsbridge Dublin 4 Dublin 4 (IE)