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(11) | EP 1 593 959 A3 |
(12) | EUROPEAN PATENT APPLICATION |
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(54) | Disposable test strips with integrated reagent/blood separation layer |
(57) An improved disposable glucose test strip for use in a test meter of the type which
receives a disposable test strip and a sample of blood from a patient and performs
an electrochemical analysis is made using a non-conductive integrated reagent/blood
separation layer containing a filler, an enzyme effective to oxidize glucose, e.g.
glucose oxidase, and a mediator effective to transfer electrons from the enzyme. The
integrated layer formulation is printed over a conductive carbon element to form a
working electrode. The filler, for example a silica filler, is selected to have a
balance of hydrophobicity such that one drying it forms a two-dimensional network
on the surface of the conductive element. The response of this test strip is essentially
temperature independent over relevant temperature ranges and is substantially insensitive
to the hematocrit of the patient.
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