(19)

(11)

EP 1 597 354 A2

(12)

(43) Date of publication: 23.11.2005 Bulletin 2005/47 (21) Application number: 04775799.2 (22) Date of filing: 24.02.2004

(51) International Patent Classification (IPC)7: C12N 1/00 (86) International application number: PCT/US2004/005518 (87) International publication number: WO 2005/007832 (27.01.2005 Gazette 2005/04)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 24.02.2003 US 450232 P (71) Applicant: CELL GENESYS, INC. South San Francisco, CA 94080 (US)	(72) Inventors: HARDING, Thomas San Francisco, CA 94131 (US) YU, De Chao Foster City, CA 94404 (US) (74) Representative: Breese Derambure Majerowicz  38, avenue de l'Opéra F-75002 Paris F-75002 Paris (FR)