Methods of producing influenza vaccine compositions

(19)

(11)

EP 1 597 400 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 2 (W2 B1)

(48)	Corrigendum issued on:
	09.10.2013 Bulletin 2013/41

(45)	Mention of the grant of the patent:
	22.08.2012 Bulletin 2012/34

(21)	Application number: 04775805.7

(22)	Date of filing: 25.02.2004

(51)

International Patent Classification (IPC):

C12Q 1/70^(2006.01)

A61K 39/145^(2006.01)

(86)	International application number:
	PCT/US2004/005697

(87)	International publication number:
	WO 2005/014862 (17.02.2005 Gazette 2005/07)

(54)	Methods of producing influenza vaccine compositions Verfahren zur Herstellung von Influenza- Impfstoffzusammensetzungen Procedes de production de compositions vaccinales contre la grippe

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

(30)

Priority:

25.02.2003 US 450181 P

(43)	Date of publication of application:
	23.11.2005 Bulletin 2005/47

(60)	Divisional application:
	12155639.3 / 2481819

(73)	Proprietor: MedImmune, LLC
	Gaithersburg MD 20878 (US)

(72)

Inventors:

TRAGER, George, Robert
San Mateo, CA 94403 (US)
KEMBLE, George
Saratoga, CA 95070 (US)
SCHWARTZ, Richard, M.
San Mateo, CA 94402 (US)
MEHTA, Harshvardhan
Fremont, CA 94555-2961 (US)
TRUONG-LE, Vu
Campbell, CA 95008 (US)
CHEN, Zhongying
Los Altos, CA 94024 (US)
PAN, Alfred, A.
Walnut Creek, CA 94598 (US)
TSAO, Eric
Potomac, MD 20854 (US)
WANG, Chiaoyin, Kathy
Sunnyvale, CA 94086 (US)
YEE, Luisa
Los Altos, CA 94022 (US)
BALU, Palani
Cupertino, CA 95014 (US)

(74)	Representative: Chapman, Paul Gilmour et al
	Marks & Clerk LLP Aurora 120 Bothwell Street Glasgow G2 7JS Glasgow G2 7JS (GB)

(56)

References cited: :

WO-A-01/22992
US-A- 3 874 999

GB-A- 660 109
US-A- 4 000 257

IKIZLER M R ET AL: "Thermostabilization of egg grown influenza viruses" VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 20, no. 9-10, 31 January 2002 (2002-01-31), pages 1393-1399, XP004334119 ISSN: 0264-410X
ARORA D J ET AL: "Concentration and purification of influenza virus from allantoic fluid." ANALYTICAL BIOCHEMISTRY JAN 1985, vol. 144, no. 1, January 1985 (1985-01), pages 189-192, XP009083195 ISSN: 0003-2697

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).