(19)
(11) EP 1 599 503 A2

(12)

(88) Date of publication A3:
21.04.2005

(43) Date of publication:
30.11.2005 Bulletin 2005/48

(21) Application number: 04717473.5

(22) Date of filing: 04.03.2004
(51) International Patent Classification (IPC)7: C07K 16/30, A61K 39/395
(86) International application number:
PCT/US2004/006719
(87) International publication number:
WO 2004/078942 (16.09.2004 Gazette 2004/38)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 04.03.2003 US 451852 P
04.03.2003 US 451856 P
06.03.2003 US 452469 P
18.04.2003 US 463801 P
24.04.2003 US 465304 P
16.05.2003 US 471177 P

(71) Applicants:
  • KIRIN BEER KABUSHIKI KAISHA
    Tokyo 104-8288 (JP)
  • GENZYME CORPORATION
    Framingham, MA 01701 (US)

(72) Inventors:
  • TEICHER, Beverly
    Ashland, MA 01721 (US)
  • ROBERTS, Bruce
    Southboro, MA 01772 (US)
  • KATAOKA, Shiro
    Takasaki-shi, Gunma 370-0044 (JP)
  • TAHARA, Tomoyuki
    Takasaki-shi, Gunma, 370-0864 (JP)
  • HONMA, Nakayuki;
    Takasaki-shi, Gunma 370-0853; (JP)

(74) Representative: Irvine, Jonquil Claire 
Marks & Clerk 4220 Nash Court Oxford Business Park South
Oxford OX4 2RU
Oxford OX4 2RU (GB)

   


(54) ENDOTHELIAL CELL SPECIFIC ANTIBODIES AND USES THEREOF