CLINICALLY RELEVANT ANIMAL MODEL OF HUMAN BREAST CANCER AND VEGF INVOLVEMENT IN DESMOPLASTIC RESPONSE, TAMOXIFEN RESISTANCE AND METASTASIS - Patent 1599577

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EP 1 599 577 A2

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(88)	Date of publication A3:
	02.06.2005

(43)	Date of publication:
	30.11.2005 Bulletin 2005/48

(21)	Application number: 04715174.1

(22)	Date of filing: 26.02.2004

(51)	International Patent Classification (IPC)⁷: C12N 1/00

(86)	International application number:
	PCT/US2004/006052

(87)	International publication number:
	WO 2004/076648 (10.09.2004 Gazette 2004/37)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
	Designated Extension States:
	AL LT LV MK

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Priority:

26.02.2003 US 449980 P

(71)	Applicant: THE UAB RESEARCH FOUNDATION
	Birmingham, AL 35294-0111 (US)

(72)	Inventors:
	QU, Zhican Birmingham, AL 35205 (US) KERN, Frances Birmingham, AL (US)

(74)	Representative: Arends, William Gerrit
	Lloyd Wise Commonwealth House 1-19 New Oxford Street London WC1A 1LW London WC1A 1LW (GB)

(54)	CLINICALLY RELEVANT ANIMAL MODEL OF HUMAN BREAST CANCER AND VEGF INVOLVEMENT IN DESMOPLASTIC RESPONSE, TAMOXIFEN RESISTANCE AND METASTASIS