(19)

(11)

EP 1 601 793 A2

(12)

(88) Date of publication A3: 13.10.2005 (43) Date of publication: 07.12.2005 Bulletin 2005/49 (21) Application number: 04716171.6 (22) Date of filing: 01.03.2004

(51) International Patent Classification (IPC)7: C12Q 1/68 (86) International application number: PCT/US2004/006337 (87) International publication number: WO 2004/078994 (16.09.2004 Gazette 2004/38)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 28.02.2003 WO PCT/US03/06198 (71) Applicant: Ravgen, Inc. Columbia, MD 21045 (US)	(72) Inventor: DHALLAN, Ravinder Bethesda, MD 20817 (US) (74) Representative: Plougmann & Vingtoft A/S  Sundkrogsgade 9, P.O. Box 831 2100 Copenhagen O 2100 Copenhagen O (DK)