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(11)

EP 1 603 897 A1

(12)

(43) Date of publication: 14.12.2005 Bulletin 2005/50 (21) Application number: 04720088.6 (22) Date of filing: 12.03.2004

(51) International Patent Classification (IPC)7: C07D 401/12, C07D 405/14, C07D 401/14, C07D 409/14, C07D 409/12, C07D 413/12, C07D 231/14, A61K 31/4155, A61P 29/00 (86) International application number: PCT/GB2004/001054 (87) International publication number: WO 2004/080999 (23.09.2004 Gazette 2004/39)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 14.03.2003 SE 0300705 26.06.2003 US 482563 P (71) Applicant: Biolipox AB 102 34 Stockholm (SE)

(72) Inventors: HALLBERG, Anders,Uppsala Univ.,Biomedical Centre S-751 23 Uppsala (SE) SCHAAL, Wesley,Biolipox AB S-102 34Stockholm (SE) LARHED, Mats,Uppsala Univ.,Biomedical Centre S-751 23 Uppsala (SE) OLOFSSON, Kristofer,Biolipox AB S-102 34 Stockholm (SE) PELCMAN, Benjamin,Biolipox AB S-10234 Stockholm (SE) SANIN, Andrei,Biolipox AB S-102 34 Stockholm (SE) (74) Representative: McNeeney, Stephen Phillip  Eric Potter Clarkson, Park View House, 58 The Ropewalk Nottingham NG1 5DD Nottingham NG1 5DD (GB)