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EP 1 603 926 A1

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(43) Date of publication: 14.12.2005 Bulletin 2005/50 (21) Application number: 04713610.6 (22) Date of filing: 23.02.2004

(51) International Patent Classification (IPC)7: C07F 9/09, C07F 9/38, C07C 305/12, C07C 307/02 (86) International application number: PCT/IB2004/000574 (87) International publication number: WO 2004/087720 (14.10.2004 Gazette 2004/42)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 10.03.2003 US 453163 P (71) Applicant: PFIZER INC. New York, N.Y. 10017 (US)

(72) Inventors: GUO, Chuangxing,Agouron Pharmaceuticals, Inc. San Diego,CA 92121 (US) DAGOSTINO, Eleanor, FerroNyalka San Diego, CA 92121 (US) DONG, Liming,Agouron Pharmaceuticals, Inc. San Diego, CA 92121 (US) HOU, Xinjun,Pfizer Global Research and Developm. Groton, CT 06340 (US) MARGOSIAK, Stephen, Anthony Escondido, CA 92025 (US) (74) Representative: Tesch, Rudolf et al c/o Pfizer GmbH, Arzneimittelwerk Gödecke Mooswaldallee 1 79090 Freiburg 79090 Freiburg (DE)