(19)

(11)

EP 1 606 312 A2

(12)

(88) Date of publication A3: 29.12.2004 (43) Date of publication: 21.12.2005 Bulletin 2005/51 (21) Application number: 04718010.4 (22) Date of filing: 05.03.2004

(51) International Patent Classification (IPC)7: C07K 14/705, C12N 15/63, A61K 38/00 (86) International application number: PCT/US2004/006779 (87) International publication number: WO 2004/081043 (23.09.2004 Gazette 2004/39)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 07.03.2003 US 452707 P 20.11.2003 US 523880 P 08.12.2003 US 528104 P (71) Applicant: Xencor Inc. Monrovia, CA 91016 (US)	(72) Inventors: DESJARLAIS, John, R. Pasadena, CA 91104 (US) ZHUKOVSKY, Eugene West Hollywood, CA 90069 (US) THOMASON, Adam Read Pasadena, CA 91106 (US) (74) Representative: Kiddle, Simon John et al Mewburn Ellis LLP York House, 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)