(19)

(11)

EP 1 608 372 A2

(12)

(88) Date of publication A3: 24.03.2005 (43) Date of publication: 28.12.2005 Bulletin 2005/52 (21) Application number: 04719527.6 (22) Date of filing: 11.03.2004

(51) International Patent Classification (IPC)7: A61K 31/4468, A61K 9/00 (86) International application number: PCT/GB2004/001037 (87) International publication number: WO 2004/080382 (23.09.2004 Gazette 2004/39)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 11.03.2003 GB 0305579 03.12.2003 GB 0328023 (71) Applicant: Arakis Ltd. Saffron Walden,Essex CB10 1KL (GB)	(72) Inventors: ROSS, Calvin,Sirus Pharmaceuticals Ltd Brixworth,Northamptonshire NN6 9UA (GB) BOOLES, Clive,Sirus Pharmaceuticals Ltd Brixworth,Northamptonshire NN6 9UA (GB) CAMPBELL, Alistair,Sirus Pharmaceuticals Ltd Brixworth,Northamptonshire NN6 9UA (GB) (74) Representative: Perry, Robert Edward et al GILL JENNINGS & EVERY Broadgate House 7 Eldon Street London EC2M 7LH London EC2M 7LH (GB)