(19)

(11)

EP 1 608 741 A2

(12)

(88) Date of publication A3: 24.02.2005 (43) Date of publication: 28.12.2005 Bulletin 2005/52 (21) Application number: 04741440.4 (22) Date of filing: 24.03.2004

(51) International Patent Classification (IPC)7: C12N 7/00, C07K 14/08 (86) International application number: PCT/EP2004/050360 (87) International publication number: WO 2004/085634 (07.10.2004 Gazette 2004/41)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 24.03.2003 EP 03075842 (71) Applicant: Akzo Nobel N.V. 6824 BM Arnhem (NL)	(72) Inventors: MUNDT, Egbert D-18461 Millienhage (DE) LETZEL, Tobias D-16225 Eberswalde (DE) PAUL, Guntram 47551 Bedburg Hau (DE) VAN LOON, Adriaan Antonius Wilhelmus Maria NL-5836 BB Sambeek (NL) (74) Representative: Mestrom, Joannes Jozef Louis  Intervet International B.V., P.O. Box 31 5830 AA Boxmeer 5830 AA Boxmeer (NL)