(19)

(11)

EP 1 611 443 A1

(12)

(43) Date of publication: 04.01.2006 Bulletin 2006/01 (21) Application number: 04725223.4 (22) Date of filing: 01.04.2004

(51) International Patent Classification (IPC):  G01N 33/543(1985.01) C12Q 1/68(1980.01) (86) International application number: PCT/SE2004/000501 (87) International publication number: WO 2004/088318 (14.10.2004 Gazette 2004/42)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL HR LT LV MK (30) Priority: 04.04.2003 US 460539 P 10.04.2003 SE 0301058 (71) Applicant: Biacore AB 754 50 Uppsala (SE)	(72) Inventors: KARLSSON, Robert S-754 40 Uppsala (SE) RICHALET-SECORDEL, Pascale Weston, VT 05161 (US) (74) Representative: Widén, Björn  Biacore AB, Rapsgatan 7 754 50 Uppsala 754 50 Uppsala (SE)