(19)
(11) EP 1 613 599 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
22.06.2011 Bulletin 2011/25

(45) Mention of the grant of the patent:
15.12.2010 Bulletin 2010/50

(21) Application number: 04725035.2

(22) Date of filing: 01.04.2004
(51) International Patent Classification (IPC): 
C07D 215/26(2006.01)
(86) International application number:
PCT/EP2004/003479
(87) International publication number:
WO 2004/087668 (14.10.2004 Gazette 2004/42)

(54)

A PROCESS FOR THE PREPARATION OF 5-(HALOACETYL)-8-(SUBSTITUTED OXY)-(1H)-QUINOLIN-2-ONES

EIN VERFAHREN ZUR HERSTELLUNG VON 5-(HALOACETYL)-8-(SUBSTITUIERTES OXY)-(1H)-CHINOLIN-2-ONEN

PROCEDE DE PREPARATION DE 5-(HALOACETYL)-8-(SUBSTITUE OXY)-(1 I H /I )-QUINOLIN-2-ONES

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
Designated Extension States:
HR LT LV MK

(30) Priority: 02.04.2003 US 459724 P

(43) Date of publication of application:
11.01.2006 Bulletin 2006/02

(73) Proprietors:
  • Novartis AG
    4056 Basel (CH)
    Designated Contracting States:
    BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR 
  • Novartis Pharma GmbH
    1230 Wien (AT)
    Designated Contracting States:
    AT 

(72) Inventors:
  • LOHSE, Olivier
    F-68170 Rixheim (FR)
  • PENN, Gerhard
    CH-4104 Oberwil (CH)
  • SCHILLING, Hanspeter
    CH-4103 Bottmingen (CH)

(74) Representative: Leon, Susanna Iris et al
Novartis AG Corporate Intellectual Property P.O. Box
4002 Basel
4002 Basel (CH)


(56) References cited: : 
EP-A- 0 052 016
WO-A-95/25104
ES-A- 8 605 239
 WO-A-00/75114
WO-A-03/042160
   
  • AMLAIKY N ET AL: "DERIVES ETHERS D'OXIMES A NOYAU CARBOSTYRILE. 4. SYNTHESES ET ACTIVITES BETA-BLOQUANTES" EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUE ELSEVIER, PARIS, FR, vol. 19, no. 4, 1984, pages 341-346, XP008033770 ISSN: 0223-5234
  • VALKENBERG M H ET AL: "Friedel-Crafts acylation of aromatics catalysed by supported ionic liquids" APPLIED CATALYSIS A: GENERAL, ELSEVIER SCIENCE, AMSTERDAM, NL, vol. 215, no. 1-2, 13 July 2001 (2001-07-13), pages 185-190, XP004246320 ISSN: 0926-860X
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).