ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCYALTRBGCZEEHUPLSKBAHRISYU........JDIM360 (Ver 1.5 21 Nov 2005) - 1991000/0 1620000/01614692EUROPEAN PATENT APPLICATIONA320060405EP05254121.620050630enenen88754020040707US2006040520061420060111200602C07K 14/47 20060101AFI20051031BHEP C07K 16/18 20060101ALI20051031BHEP G01N 33/564 20060101ALI20051031BHEP deME-5, ME-2, and EPP2: menschliche Proteinantigene, die mit Autoantikörpern reagieren, die im Serum von Frauen vorliegen, die an Endometrose leidenenME-5, ME-2, and EPP2: human protein antigens reactive with autoantibodies present in the serum of women suffering from endometriosisfrME-5, ME-2, and EPP2: protéines humaines antigéniques réactives contre des autoanticorps présents dans le serum de femmes atteintes d'endométrioseNONEDIAGNOSTIC PRODUCTS CORPORATION00728210N.95139 PJC5700 West 96th StreetLos Angeles California 90045USSaid El Shami, A11016 Red Barn RoadCamarillo, CA 93012USCampbell, Bruce26005-F Alizia Canyon DriveCalabasas, CA 91302USSustarsic, Dennis4288 Candleberry AvenueSeal Beach, CA 90740USSahakian, Niver4171 Green Meadow CourtEnciino, CA 91316USCampbell, Patrick John Henry00080141J.A. Kemp & Co., 14 South Square, Gray's InnLondon WC1R 5JJGBATBEBGCHCYCZDEDKEEESFIFRGBGRHUIEISITLILTLUMCNLPLPTROSESISKTRALBAHRLVMKYU20060405200614

Three human endometrial antigens, ME-5; ME-2 and EPP2, and combination thereof have been discovered that are the targets of antibodies present in the serum of women suffering from endometriosis. These protein products and the human antibodies reactive with them are used as tools for diagnostic assays that monitor patients with the disease of endometriosis.