(19)

(11)

EP 1 615 637 A1

(12)

(43) Date of publication: 18.01.2006 Bulletin 2006/03 (21) Application number: 04725885.0 (22) Date of filing: 06.04.2004

(51) International Patent Classification (IPC):  A61K 31/4196(2000.01) A61P 3/00(2000.01) C07D 249/12(1985.01) A61P 3/10(2000.01) (86) International application number: PCT/DK2004/000249 (87) International publication number: WO 2004/089367 (21.10.2004 Gazette 2004/43)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL HR LT LV MK (30) Priority: 11.04.2003 DK 200300566 02.05.2003 US 467362 P (71) Applicant: NOVO NORDISK A/S 2880 Bagsvaerd (DK)	(72) Inventors: ANDERSEN, Henrik, Sune Kgs. Lyngby, 2800 (DK) KAMPEN, Gita, Camilla, Tejlgaard N rum, 2850 (DK) CHRISTENSEN, Inge, Th ger Kgs. Lyngby, 2800 (DK) MOGENSEN, John Patrick Herlev, 2730 (DK) LARSEN, Annette Rosendal Kgs. Lyngby, 2800 (DK) (74) Representative: Madsen, Inger Margrethe Schelde et al Novo Nordisk A/S, Corporate Patents, Novo Alle 2880 Bagsvaerd 2880 Bagsvaerd (DK)