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(11)

EP 1 620 405 A2

(12)

(88) Date of publication A3: 14.04.2005 (43) Date of publication: 01.02.2006 Bulletin 2006/05 (21) Application number: 04751090.4 (22) Date of filing: 29.04.2004

(51) International Patent Classification (IPC):  C07D 231/14(1985.01) C07D 231/20(1985.01) C07D 231/24(1985.01) C07D 401/12(1990.01) A61K 31/415(1985.01) C07D 231/22(1985.01) C07D 401/04(1990.01) (86) International application number: PCT/US2004/013530 (87) International publication number: WO 2004/099154 (18.11.2004 Gazette 2004/47)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 01.05.2003 US 427847 (71) Applicant: ABBOTT LABORATORIES Abbott Park, Illinois 60064-6008 (US)

(72) Inventors: ATKINSON, Robert N. Raleigh, NC 27613 (US) DRIZEN, Irene Wadsworth, Illinois 60083 (US) GREGG, Robert J. Libertyville, IL 60048 (US) GROSS, Michael F. Durham, North Carolina 27703 (US) KORT, Michael E. Lake Bluff, Illinois 60044 (US) SHI, Lei Waukegan, Illinois 60087 (US) (74) Representative: Modiano, Micaela Nadia et al Modiano, Josif, Pisanty & Staub Ltd., Baaderstrasse 3 80469 München 80469 München (DE)