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EP 1 620 464 A1

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(43) Date of publication: 01.02.2006 Bulletin 2006/05 (21) Application number: 04730429.0 (22) Date of filing: 30.04.2004

(51) International Patent Classification (IPC):  C07K 14/595(1995.01) A61K 38/33(1995.01) C12N 15/09(1990.01) A61P 3/10(2000.01) C07K 14/50(1995.01) A61K 38/18(1995.01) A01K 67/027(1990.01) (86) International application number: PCT/CA2004/000648 (87) International publication number: WO 2004/096853 (11.11.2004 Gazette 2004/46)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 30.04.2003 US 509068 P (71) Applicant: Waratah Pharmaceuticals, Inc. Toronto, Ontario M5B 2E7 (CA)	(72) Inventors: BRAND, Stephen J, Lincoln, MA 01773 (US) CRUZ, Antonio Toronto, Ontario M5P 2T7 (CA) (74) Representative: Holliday, Louise Caroline  D Young & Co 120 Holborn London EC1N 2DY London EC1N 2DY (GB)