(19)

(11)

EP 1 620 735 A1

(12)

(43) Date of publication: 01.02.2006 Bulletin 2006/05 (21) Application number: 04729080.4 (22) Date of filing: 23.04.2004

(51) International Patent Classification (IPC):  G01N 33/68(1980.01) (86) International application number: PCT/EP2004/004350 (87) International publication number: WO 2004/097424 (11.11.2004 Gazette 2004/46)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 25.04.2003 US 465369 P (71) Applicants: Genova Ltd. Hamilton HM12 (BM) Novartis Pharma GmbH 1230 Wien (AT) AT	(72) Inventors: BOUGUELERET, Lydie CH-1217 Meyrin (CH) REFFAS, Samia CH-1217 Meyrin (CH) (74) Representative: Leon, Susanna Iris et al Novartis AG Corporate Intellectual Property P.O. Box 4002 Basel 4002 Basel (CH)