(19)

(11)

EP 1 622 455 A2

(12)

(88) Date of publication A3: 03.02.2005 (43) Date of publication: 08.02.2006 Bulletin 2006/06 (21) Application number: 04751195.1 (22) Date of filing: 30.04.2004

(51) International Patent Classification (IPC):  A01N 45/00(1985.01) C07C 1/00(1968.09) (86) International application number: PCT/US2004/013703 (87) International publication number: WO 2004/098522 (18.11.2004 Gazette 2004/47)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: LT LV (30) Priority: 30.04.2003 US 466638 P (71) Applicants: Bioxell S.p.a. 20132 Milano (IT) UNIVERSITY OF CHICAGO Chicago, IL 60637 (US)	(72) Inventors: ADORINI, Luciano I-20133 Milano (IT) PENNA, Guiseppe I-20095 Cusano (IT) USKOKOVIC, Milan, R. Upper Montclair, NJ 07043 (US) MAEHR, Hubert Wayne, NJ 07470 (US) LI, Yan, Chun Chicago, IL60637 (US) (74) Representative: Teuten, Andrew John et al Sagittarius Intellectual Property Consultants Ltd Taylor House 39 High Street Marlow, Bucks. SL7 1AF Marlow, Bucks. SL7 1AF (GB)