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(11)

EP 1 622 578 A2

(12)

(88) Date of publication A3: 27.01.2005 (43) Date of publication: 08.02.2006 Bulletin 2006/06 (21) Application number: 04751700.8 (22) Date of filing: 10.05.2004

(51) International Patent Classification (IPC):  A61K 8/18(0000.00) A61K 8/30(0000.00) (86) International application number: PCT/US2004/014434 (87) International publication number: WO 2004/100906 (25.11.2004 Gazette 2004/48)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 08.05.2003 US 468748 P 09.05.2003 US 469554 P 31.10.2003 US 516040 P (71) Applicant: THE PROCTER & GAMBLE COMPANY Cincinnati, Ohio 45202 (US)

(72) Inventors: CLAPP, Mannie, Lee Mason, OH 45040 (US) TAYLOR, Rebecca, Ann Fairfield, OH 45014 (US) BARFORD, Brian, Dale West Chester, OH 45069 (US) SUNKEL, Jorge, Max Cincinnati, OH 45219 (US) WEI, Karl, Shiqing Mason, OH 45040 (US) THOMAS, Cheyne, Pohlman Independence, KY 41051 (US) (74) Representative: Wilding, Richard Alan et al Procter & Gamble Technical Centres Limited Patent Department Rusham Park Whitehall Lane Egham, Surrey TW20 9NW Egham, Surrey TW20 9NW (GB)