(19)

(11)

EP 1 623 211 A2

(12)

(88) Date of publication A3: 24.03.2005 (43) Date of publication: 08.02.2006 Bulletin 2006/06 (21) Application number: 04750558.1 (22) Date of filing: 23.04.2004

(51) International Patent Classification (IPC):  G01N 21/47(1980.01) G01N 15/06(1968.09) G01N 25/58(1968.09) G01N 33/00(1968.09) (86) International application number: PCT/US2004/012614 (87) International publication number: WO 2004/097370 (11.11.2004 Gazette 2004/46)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 25.04.2003 WO PCT/US03/13181 11.03.2004 US 799000 (71) Applicant: Prometheus Biosciences, Inc. Los Altos, CA 94022 (US)	(72) Inventors: HEFTI, John, J. San Francisco, CA 94118 (US) DRAKO, Dean, M. Woodside, CA 94062 (US) (74) Representative: Viering, Jentschura & Partner  Steinsdorfstrasse 6 80538 München 80538 München (DE)