(19)
(11) EP 1 625 163 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
02.11.2011 Bulletin 2011/44

(45) Mention of the grant of the patent:
31.08.2011 Bulletin 2011/35

(21) Application number: 04732278.9

(22) Date of filing: 12.05.2004
(51) International Patent Classification (IPC): 
C07K 16/26(2006.01)
G01N 33/68(2006.01)
C12N 5/20(2006.01)
 G01N 33/531(2006.01)
G01N 33/74(2006.01)
(86) International application number:
PCT/EP2004/005091
(87) International publication number:
WO 2004/099252 (18.11.2004 Gazette 2004/47)

(54)

METHOD OF DETECTING PROBNP WITH A MONOCLONAL ANTIBODY BINDING TO THE AMINO ACIDS 38-43

VERFAHREN ZUM NACHWEIS VON PROBNP MIT EINEM MONOKLONALEN ANTIKÖRPER, DER DIE AMINO SAÜRE 38-43 BINDET

METHODE DE DETECTION DU PROBNP A L'AIDE D'UN ANTICORPS MONOCLONAL LIANT LES ACIDES AMINES 38 A 43

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

(30) Priority: 12.05.2003 EP 03010591

(43) Date of publication of application:
15.02.2006 Bulletin 2006/07

(73) Proprietors:
  • Roche Diagnostics GmbH
    68305 Mannheim (DE)
    Designated Contracting States:
    DE 
  • F.Hoffmann-La Roche AG
    4070 Basel (CH)
    Designated Contracting States:
    AT BE BG CH CY CZ DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR 

(72) Inventors:
  • KLEMT, Volker
    82362 Weilheim (DE)
  • BORGYA, Anneliese
    82402 Seeshaupt (DE)
  • GALLUSSER, Andreas
    82377 Penzberg (DE)
  • GROL, Michael
    82340 Feldafing (DE)
  • HALLERMAYER, Klaus
    82340 Feldafing (DE)
  • SEIDEL, Christoph
    82362 Weilheim (DE)


(56) References cited: : 
WO-A-00/35951
   
  • HUGHES D ET AL: "An immunoluminometric asay for N-terminal pro-brain natriuretic peptide: develop,ment of a test for left venticular dysfunction" CLINICAL SCIENCE, BIOCHEMICAL SOCIETY AND THE MEDICAL RESEARCH SOCIETY, LONDON,, GB, vol. 96, no. 4, April 1999 (1999-04), pages 373-380, XP002136252 ISSN: 0143-5221 cited in the application
  • PEMBERTON C J ET AL: "AMINO-TERMINAL PROBNP IN OVINE PLASMA: EVIDENCE FOR ENHANCED SECRETION IN RESPONSE TO CARDIAC OVERLOAD" AMERICAN JOURNAL OF PHYSIOLOGY, AMERICAN PHYSIOLOGICAL SOCIETY, BETHESDA, MD, US, vol. 275, no. 4, PART 2, 1998, pages H1200-H1208, XP000913587 ISSN: 0002-9513
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).