(19)

(11)

EP 1 626 986 A2

(12)

(88) Date of publication A3: 20.01.2005 (43) Date of publication: 22.02.2006 Bulletin 2006/08 (21) Application number: 04732961.0 (22) Date of filing: 14.05.2004

(51) International Patent Classification (IPC):  C07K 14/47(1995.01) G01N 33/53(1985.01) C07K 16/18(1995.01) G01N 33/50(1980.01) (86) International application number: PCT/EP2004/005195 (87) International publication number: WO 2004/101615 (25.11.2004 Gazette 2004/48)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 16.05.2003 US 471061 P (71) Applicants: Genova Ltd. Hamilton HM12 (BM) Novartis Pharma GmbH 1230 Wien (AT) AT	(72) Inventors: BOUGUELERET, Lydie 1217 Meyrin (CH) MAHE, Eve 1217 Meyrin (CH) (74) Representative: Leon, Susanna Iris et al Novartis AG Corporate Intellectual Property P.O. Box 4002 Basel 4002 Basel (CH)