(19)

(11)

EP 1 628 681 A1

(12)

(43) Date of publication: 01.03.2006 Bulletin 2006/09 (21) Application number: 04776169.7 (22) Date of filing: 27.05.2004

(51) International Patent Classification (IPC):  A61K 41/00(1985.01) (86) International application number: PCT/US2004/016958 (87) International publication number: WO 2005/000352 (06.01.2005 Gazette 2005/01)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 04.06.2003 US 475945 P (71) Applicant: Vector Tobacco Ltd. Hamilton HM 11, Bermuda (BM)	(72) Inventor: CONKLING, Mark Chapel Hill, NC 27516 (US) (74) Representative: Plougmann & Vingtoft A/S  Sundkrogsgade 9, P.O. Box 831 2100 Copenhagen O 2100 Copenhagen O (DK)