(19)

(11)

EP 1 629 094 A1

(12)

(43) Date of publication: 01.03.2006 Bulletin 2006/09 (21) Application number: 04733841.3 (22) Date of filing: 19.05.2004

(51) International Patent Classification (IPC):  C12N 9/12(1980.01) C12Q 1/48(1980.01) C07K 14/31(1995.01) (86) International application number: PCT/GB2004/002158 (87) International publication number: WO 2004/104192 (02.12.2004 Gazette 2004/49)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 22.05.2003 GB 0311789 (71) Applicant: AstraZeneca AB 151 85 Södertälje (SE)	(72) Inventor: DOIG, Peter Clifford Waltham, MA 02451 (US)