(19)

(11)

EP 1 629 282 A2

(12)

(88) Date of publication A3: 28.04.2005 (43) Date of publication: 01.03.2006 Bulletin 2006/09 (21) Application number: 04731927.2 (22) Date of filing: 10.05.2004

(51) International Patent Classification (IPC):  G01N 33/68(1980.01) C12N 9/48(1980.01) (86) International application number: PCT/EP2004/004964 (87) International publication number: WO 2004/104595 (02.12.2004 Gazette 2004/49)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 22.05.2003 EP 03011593 (71) Applicant: Bayer HealthCare AG 51368 Leverkusen (DE)	(72) Inventors: GOLZ, Stefan 45326 Essen (DE) BRÜGGEMEIER, Ulf 42799 Leichlingen (DE) GEERTS, Andreas 42113 Wuppertal (DE)