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(11)

EP 1 631 265 A2

(12)

(88) Date of publication A3: 09.06.2005 (43) Date of publication: 08.03.2006 Bulletin 2006/10 (21) Application number: 04735180.4 (22) Date of filing: 28.05.2004

(51) International Patent Classification (IPC):  A61K 31/00(1985.01) A61K 31/65(1985.01) A61K 31/196(2000.01) A61K 31/192(2000.01) A61K 31/722(2000.01) A61K 31/717(2000.01) A61K 31/337(2000.01) A61K 31/42(1985.01) A61K 31/734(2000.01) A61K 31/573(2000.01) A61K 31/18(1985.01) A61K 31/366(2000.01) A61K 31/718(2000.01) A61K 31/519(2000.01) A61K 31/436(2000.01) (86) International application number: PCT/CA2004/000800 (87) International publication number: WO 2004/105737 (09.12.2004 Gazette 2004/50)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 30.05.2003 US 474907 P 10.06.2003 US 477654 P 22.09.2003 US 505258 P 22.09.2003 US 505257 P 17.11.2003 US 520804 P 17.11.2003 US 520574 P 17.11.2003 US 520808 P 11.12.2003 US 529136 P 31.12.2003 US 533669 P (71) Applicant: ARC PHARMACEUTICALS, INC. Vancouver, British Columbia V6T 1Z3 (CA)

(72) Inventors: CASHMAN, Johanne Vancouver, British Columbia V6N 1R1 (CA) SPRINGATE, Christopher Vancouver, British Columbia V5T 2H5 (CA) HAY, Bruce Vancouver, British Columbia V6S 2K8 (CA) WINTERNITZ, Charles Delta, British Columbia V4K 3L2 (CA) (74) Representative: Stolmár, Matthias et al Stolmár Scheele Hinkelmann, Blumenstrasse 17 80331 München 80331 München (DE)