(19)

(11)

EP 1 631 597 A2

(12)

(88) Date of publication A3: 09.06.2005 (43) Date of publication: 08.03.2006 Bulletin 2006/10 (21) Application number: 04752449.1 (22) Date of filing: 17.05.2004

(51) International Patent Classification (IPC):  C08F 2/00(1974.07) C08B 37/00(1974.07) (86) International application number: PCT/US2004/015435 (87) International publication number: WO 2004/105685 (09.12.2004 Gazette 2004/50)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL HR LT LV MK (30) Priority: 22.05.2003 US 473294 P (71) Applicant: Gryphon Therapeutics, Inc. South San Francisco, CA 94080-7014 (US)	(72) Inventors: LOW, Donald Burlingame, CA 94010 (US) HU, Ying Millbrae, CA 94030 (US) BOTTI, Paolo I-29100 Piacenza (IT) (74) Representative: Thomson, Paul Anthony  Potts, Kerr & Co. 15, Hamilton Square Birkenhead Merseyside CH41 6BR Birkenhead Merseyside CH41 6BR (GB)