(19)

(11)

EP 1 631 679 A2

(12)

(88) Date of publication A3: 09.06.2005 (43) Date of publication: 08.03.2006 Bulletin 2006/10 (21) Application number: 04732297.9 (22) Date of filing: 12.05.2004

(51) International Patent Classification (IPC):  C12Q 1/37(1990.01) G01N 33/574(1985.01) (86) International application number: PCT/EP2004/005069 (87) International publication number: WO 2004/104215 (02.12.2004 Gazette 2004/49)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 21.05.2003 EP 03011482 (71) Applicant: Bayer HealthCare AG 51368 Leverkusen (DE)	(72) Inventors: GOLZ, Stefan 45326 Essen (DE) BRÜGGEMEIER, Ulf 42799 Leichlingen (DE) SUMMER, Holger 42113 Wuppertal (DE)