(19)

(11)

EP 1 631 687 A2

(12)

(88) Date of publication A3: 22.09.2005 (43) Date of publication: 08.03.2006 Bulletin 2006/10 (21) Application number: 04760178.6 (22) Date of filing: 22.04.2004

(51) International Patent Classification (IPC):  C12Q 1/68(1980.01) C07K 14/705(1995.01) (86) International application number: PCT/US2004/012788 (87) International publication number: WO 2004/094671 (04.11.2004 Gazette 2004/45)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL HR LT LV MK (30) Priority: 22.04.2003 US 464586 P 22.04.2003 US 464588 P (71) Applicants: Coley Pharmaceutical GmbH 40764 Langenfeld (DE) Coley Pharmaceutical Group, Inc. Wellesley, MA 02481 (US)	(72) Inventors: VOLLMER, Jörg D-40591 Duesseldorf (DE) JURK, Marion D-41540 Dormagen (DE) LIPFORD, Grayson, B. Watertown, MA 02472 (US) SCHETTER, Christian D-40723 Hilden (DE) FORSBACH, Alexandra D-40764 Rantingen (DE) KRIEG, Arthur, M. Wellesley, MA 02482 (US) (74) Representative: Jump, Timothy John Simon et al Venner Shipley LLP 20 Little Britain London EC1A 7DH London EC1A 7DH (GB)