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EP 1 633 710 A1

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(43) Date of publication: 15.03.2006 Bulletin 2006/11 (21) Application number: 04753845.9 (22) Date of filing: 02.06.2004

(51) International Patent Classification (IPC):  C07D 209/46(1985.01) C07D 403/12(1990.01) A61K 31/4035(2000.01) C07D 413/12(1990.01) C07D 417/12(1990.01) A61P 35/04(2000.01) (86) International application number: PCT/US2004/017105 (87) International publication number: WO 2004/108672 (16.12.2004 Gazette 2004/51)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 02.06.2003 US 452701 (71) Applicant: ABBOTT LABORATORIES Abbott Park, Illinois 60064-6008 (US)

(72) Inventors: CURTIN, Michael, L. Pleasant Prairie, WI 53158 (US) DAVIDSEN, Steven, K Libertyville, IL 60048 (US) FREY, Robin, R. Libertyville, IL 60048 (US) HEYMAN, Howard, R. Deerfield, IL 60015 (US) HOLMS, James, H. Gurnee, IL 60031 (US) MICHAELIDES, Michael Libertyville, IL 60048 (US) STEINMAN, Douglas, H. Morton Grove, IL 60053 (US) (74) Representative: Modiano, Micaela Nadia et al Modiano, Josif, Pisanty & Staub Ltd., Baaderstrasse 3 80469 München 80469 München (DE)