(19)

(11)

EP 1 635 809 A1

(12)

(43) Date of publication: 22.03.2006 Bulletin 2006/12 (21) Application number: 04755657.6 (22) Date of filing: 18.06.2004

(51) International Patent Classification (IPC):  A61K 31/20(1985.01) C07C 61/08(1968.09) (86) International application number: PCT/US2004/019616 (87) International publication number: WO 2004/112774 (29.12.2004 Gazette 2004/53)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: HR MK (30) Priority: 20.06.2003 US 600189 04.09.2003 US 656567 (71) Applicant: METABOLEX, INC. Hayward, CA 94545-3619 (US)	(72) Inventor: DAUGS, Edward, D. Midland, MI 48642 (US) (74) Representative: Thomson, Paul Anthony et al Potts, Kerr & Co. 15, Hamilton Square Birkenhead Merseyside CH41 6BR Birkenhead Merseyside CH41 6BR (GB)