(19)

(11)

EP 1 636 256 A2

(12)

(88) Date of publication A3: 24.02.2005 (43) Date of publication: 22.03.2006 Bulletin 2006/12 (21) Application number: 04785771.9 (22) Date of filing: 30.03.2004

(51) International Patent Classification (IPC):  C07K 14/415(1995.01) C07K 14/56(1995.01) C07K 14/565(1995.01) (86) International application number: PCT/US2004/009824 (87) International publication number: WO 2005/003157 (13.01.2005 Gazette 2005/02)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 10.06.2003 US 477246 P 24.07.2003 US 489725 P 30.09.2003 WO PCT/US03/30802 30.09.2003 US 676705 (71) Applicant: Xencor, Inc. Monrovia, CA 91016 (US)

(72) Inventors: AGUINALDO, Anna Marie Altadena, California 91001 (US) BEYNA, Amelia, Joy Cheverly, Maryland 20785 (US) CHO, Ho, Sung Monrovia, California 91016 (US) DESJARLAIS, John, Rudolph Pasadena, California 91104 (US) MARSHALL, Shannon, Alicia San Francisco, California 94122 (US) MUCHHAL, Umesh Monrovia, California 91016 (US) VILLEGAS, Michael, Francis, Aquino Los Angeles, California 90041 (US) ZHUKOVSKY, Eugene West Hollywood, California 90069 (US) QUESENBERRY, Michael, Stephen Los Angeles, California 91017 (US) (74) Representative: Kiddle, Simon John et al Mewburn Ellis LLP York House, 23 Kingsway London WC2B 6HP London WC2B 6HP (GB)