(19)

(11)

EP 1 636 258 A2

(12)

(88) Date of publication A3: 10.02.2005 (43) Date of publication: 22.03.2006 Bulletin 2006/12 (21) Application number: 04739768.2 (22) Date of filing: 09.06.2004

(51) International Patent Classification (IPC):  C07K 14/47(1995.01) A61K 38/17(1995.01) (86) International application number: PCT/EP2004/006265 (87) International publication number: WO 2004/111088 (23.12.2004 Gazette 2004/52)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 10.06.2003 US 477470 P 16.09.2003 US 503388 P (71) Applicant: Xantos Biomedicine AG 81377 München (DE)

(72) Inventors: GILLE, Hendrik 81371 München (DE) GAWIN, Beate 81369 München (DE) SCHÄFER, Rolf 82061 Neuried (DE) HESS, Stephan 80335 München (DE) KORHERR, Christian 82152 Martinsried (DE) BOCHE, Irene 81379 München (DE) WALTER, Theresia 06179 Zappendorf (DE) GNIRKE, Andreas 82131 Gauting (DE) (74) Representative: Bösl, Raphael Konrad  Patentanwälte Isenbruck Bösl Hörschler Wichmann Huhn Prinzregentenstrasse 68 81675 München 81675 München (DE)