(19)
(11)
EP 1 636 264 A2
(12)
(88)
Date of publication A3:
17.03.2005
(43)
Date of publication:
22.03.2006
Bulletin 2006/12
(21)
Application number:
04740252.4
(22)
Date of filing:
24.06.2004
(51)
International Patent Classification (IPC):
C07K
14/705
(1995.01)
A61K
39/00
(1985.01)
(86)
International application number:
PCT/EP2004/006838
(87)
International publication number:
WO 2004/113387
(
29.12.2004
Gazette 2004/53)
(84)
Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
(30)
Priority:
24.06.2003
EP 03014121
(71)
Applicant:
Merck Patent GmbH
64293 Darmstadt (DE)
(72)
Inventors:
BAKER, Matthew
Hornigsea Cambridge CB5 9JG (GB)
HELLENDOORN, Koen
Suffolk CB8 7AT (GB)
(54)
TUMOUR NECROSIS FACTOR RECEPTOR MOLECULES WITH REDUCED IMMUNOGENICITY