(19)
(11) EP 1 636 364 A2

(12)

(88) Date of publication A3:
27.10.2005

(43) Date of publication:
22.03.2006 Bulletin 2006/12

(21) Application number: 04785931.9

(22) Date of filing: 07.06.2004
(51) International Patent Classification (IPC): 
C12N 15/11(1990.01)
A61P 27/00(2000.01)
 A61K 31/713(2000.01)
A61P 37/00(2000.01)
(86) International application number:
PCT/US2004/018012
(87) International publication number:
WO 2005/007853 (27.01.2005 Gazette 2005/04)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
Designated Extension States:
AL HR LT LV MK

(30) Priority: 06.06.2003 US 476194 P
22.09.2003 US 504731 P
10.12.2003 US 528249 P
31.03.2004 US 557671 P
02.06.2004 US 575814 P

(71) Applicant: Senesco Technologies, Inc.
New Brunswick, NJ 08901 (US)

(72) Inventors:
  • THOMPSON, John, E.
    Waterloo, Ontario N2K 4N1 (CA)
  • TAYLOR, Catherine
    Waterloo, Ontario N2K 3N1 (CA)

(74) Representative: Baldock, Sharon Claire et al
BOULT WADE TENNANT, Verulam Gardens 70 Gray's Inn Road
London WC1X 8BT
London WC1X 8BT (GB)

   


(54) INHIBITION OF APOPTOSIS-SPECIFIC ELF-5A ( EIF-5A1) WITH ANTISENSE OLIGONUCLEOTIDES AND SIRNAS AS ANTI-INFLAMMATORY THERAPEUTICS