(19)

(11)

EP 1 636 377 A2

(12)

(88) Date of publication A3: 26.05.2005 (43) Date of publication: 22.03.2006 Bulletin 2006/12 (21) Application number: 04736923.6 (22) Date of filing: 16.06.2004

(51) International Patent Classification (IPC):  C12Q 1/68(1980.01) C07K 14/47(1995.01) C12N 15/12(1990.01) A23K 1/18(1968.09) (86) International application number: PCT/GB2004/002559 (87) International publication number: WO 2004/113570 (29.12.2004 Gazette 2004/53)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 16.06.2003 GB 0313964 (71) Applicant: MARS, INCORPORATED McLean, Virginia 22101-3883 (US)	(72) Inventors: JONES, Paul Glyn, Masterfoods Melton Mowbray, Leics LE13 1BB (GB) FRETWELL, Neale, Masterfoods Melton Mowbray, Leics LE13 1BB (GB) (74) Representative: Woods, Geoffrey Corlett  J.A. KEMP & CO. Gray's Inn 14 South Square London WC1R 5JJ London WC1R 5JJ (GB)