(19)
(11) EP 1 641 458 A2

(12)

(88) Date of publication A3:
12.01.2006

(43) Date of publication:
05.04.2006 Bulletin 2006/14

(21) Application number: 03782372.1

(22) Date of filing: 11.12.2003
(51) International Patent Classification (IPC): 
A61K 31/502(2000.01)
A61P 35/00(2000.01)
 A61K 31/44(1985.01)
(86) International application number:
PCT/EP2003/014071
(87) International publication number:
WO 2004/058234 (15.07.2004 Gazette 2004/29)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 27.12.2002 EP 02090431
12.03.2003 EP 03090061

(71) Applicant: Schering Aktiengesellschaft
13342 Berlin (DE)

(72) Inventors:
  • SCHUPPAN, Detlef
    91054 Erlangen (DE)
  • HEROLD, Christoph
    90518 Altdorf (DE)
  • GANSMAYER, Marion
    91054 Erlangen (DE)
  • OCKER, Matthias
    91083 Baiersdorf (DE)
  • THIERAUCH, Karl-Heinz
    14169 Berlin (DE)

   


(54) PHARMACEUTICAL COMBINATIONS OF PHTHALAZINE VEGF INHIBITORS AND BENZAMIDE HDAC INHIBITORS