(19)

(11)

EP 1 642 138 A1

(12)

(43) Date of publication: 05.04.2006 Bulletin 2006/14 (21) Application number: 04763049.6 (22) Date of filing: 29.06.2004

(51) International Patent Classification (IPC):  G01N 33/68(1980.01) C07K 19/00(1995.01) C07K 14/515(1995.01) C07K 16/22(1995.01) (86) International application number: PCT/EP2004/007048 (87) International publication number: WO 2005/003782 (13.01.2005 Gazette 2005/02)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 30.06.2003 US 484211 P (71) Applicants: Genova Ltd. Hamilton HM12 (BM) Novartis Pharma GmbH 1235 Vienna (AT) AT	(72) Inventors: BOUGUELERET, Lydie 1213 Petit-Lancy (CH) NIKNEJAD, Anne 1293 Bellevu (CH) (74) Representative: de Weerd, Petrus G.W.  Novartis AG Corporate Intellectual Property 4002 Basel 4002 Basel (CH)