(19)

(11)

EP 1 642 194 A2

(12)

(43) Date of publication: 05.04.2006 Bulletin 2006/14 (21) Application number: 04756652.6 (22) Date of filing: 02.07.2004

(51) International Patent Classification (IPC):  G06F 1/00(1968.09) (86) International application number: PCT/US2004/021494 (87) International publication number: WO 2005/008379 (27.01.2005 Gazette 2005/04)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL HR LT LV MK (30) Priority: 03.07.2003 US 613623 03.07.2003 US 613706 (71) Applicant: REACTION DESIGN San Diego, CA 92121 (US)	(72) Inventors: MCRAE, Gregory, J. Winchester, MA 01890 (US) WANG, Cheng-nan San Diego, CA 92126 (US) (74) Representative: Viering, Jentschura & Partner  Steinsdorfstrasse 6 80538 München 80538 München (DE)