(19)

(11)

EP 1 644 488 A1

(12)

(43) Date of publication: 12.04.2006 Bulletin 2006/15 (21) Application number: 04743366.9 (22) Date of filing: 13.07.2004

(51) International Patent Classification (IPC):  C12N 5/06(1990.01) A61K 41/00(1985.01) (86) International application number: PCT/GB2004/003025 (87) International publication number: WO 2005/007837 (27.01.2005 Gazette 2005/04)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 14.07.2003 GB 0316431 (71) Applicant: CELLFACTORS PLC Cambridge CB2 4AT (GB)

(72) Inventors: PHILLIPS, Ian Claremont Crescent, Sheffield S10 2TA (GB) GANGEMI, Lavinia Claremont Crescent, Sheffield S10 2TA (GB) KIBRIA, Mohamed Kiron Claremont Crescent, Sheffield S10 2TA (GB) STRINGER, Bradley Claremont Crescent, Sheffield S10 2TA (GB) WEST, William Cellfactors Plc Imperial Way, Newport NP10 8UH (GB) PANDYA, Anant Croydon CR0 5DJ (GB) SIEPLE, Christine Leeplace, Pulborough RH20 1DF (GB) (74) Representative: Davies, Jonathan Mark  Reddie & Grose 16 Theobalds Road London WC1X 8PL London WC1X 8PL (GB)