(19)

(11)

EP 1 646 624 A1

(12)

(43) Date of publication: 19.04.2006 Bulletin 2006/16 (21) Application number: 04743337.0 (22) Date of filing: 09.07.2004

(51) International Patent Classification (IPC):  C07D 403/04(1990.01) A61K 31/404(2000.01) C07D 409/04(1990.01) A61P 29/00(2000.01) (86) International application number: PCT/GB2004/002996 (87) International publication number: WO 2005/005415 (20.01.2005 Gazette 2005/03)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: LT LV (30) Priority: 09.07.2003 US 485390 P 09.07.2003 SE 0302035 (71) Applicant: Biolipox AB 102 34 Stockholm (SE)

(72) Inventors: OLOFSSON, Kristofer, Biolipox AB S-102 34 Stockholm (SE) SUNA, E., Latvian Institute of Organics Synthesis LV-1006 Riga (LV) PELCMAN, Benjamin, Biolipox AB S-10234 Stockholm (SE) OZOLA, V., Latvian Institute of Organic Synthesis LV-1006 Riga (LV) KATKEVICS, M., Latvian Inst. of Organic Synthesis LV-1006 Riga (LV) KALVINS, I., Latvian Inst. of Organic Synthesis LV-1006 Riga (LV) Schaal, Wesley. S-102 34 Stockholm (SE) (74) Representative: McNeeney, Stephen Phillip  Eric Potter Clarkson LLP Park View House 58 The Ropewalk Nottingham NG1 5DD Nottingham NG1 5DD (GB)