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(11)

EP 1 648 938 A1

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(43) Date of publication: 26.04.2006 Bulletin 2006/17 (21) Application number: 04743640.7 (22) Date of filing: 30.07.2004

(51) International Patent Classification (IPC):  C07K 14/82(1995.01) C12N 15/12(1990.01) A61P 35/00(2000.01) C12N 15/11(1990.01) C07K 16/32(1995.01) (86) International application number: PCT/GB2004/003326 (87) International publication number: WO 2005/012357 (10.02.2005 Gazette 2005/06)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 31.07.2003 GB 0317988 (71) Applicant: THE UNIVERSITY OF YORK York Y01 5DD (GB)	(72) Inventors: MILMER, Jo, Department of Biology York, YO1 5DD (GB) JIANG, Ming, Department of Biology York, YO1 5DD (GB) (74) Representative: Harrison, Michael Robert  Harrison Goddard Foote 40-43 Chancery Lane London WC2A 1JA London WC2A 1JA (GB)