(19)

(11)

EP 1 651 235 A2

(12)

(88) Date of publication A3: 07.07.2005 (43) Date of publication: 03.05.2006 Bulletin 2006/18 (21) Application number: 04757425.6 (22) Date of filing: 05.08.2004

(51) International Patent Classification (IPC):  A61K 31/56(1985.01) (86) International application number: PCT/US2004/025295 (87) International publication number: WO 2005/016276 (24.02.2005 Gazette 2005/08)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR Designated Extension States: AL HR LT LV MK (30) Priority: 05.08.2003 US 492769 P (71) Applicants: Samaritan Pharmaceuticals, Inc. Las Vegas, NV 89109 (US) GEORGETOWN UNIVERSITY Washington, DC 20007-1408 (US) Papadopoulos, Vassilios North Potomac, MD 20878 (US) Lecanu, Laurent McLean, VA 22102 (US) Greeson, Janet Las Vegas, NV 89109 (US)

(72) Inventors: PAPADOPOULOS, Vassilios North Potomac, MD 20878 (US) LECANU, Laurent McLean, VA 22102 (US) GREESON, Janet Las Vegas, NV 89109 (US) (74) Representative: Lucas, Brian Ronald et al Lucas & Co. 135 Westhall Road Warlingham Surrey CR6 9HJ Warlingham Surrey CR6 9HJ (GB)