(19)

(11)

EP 1 651 634 A1

(12)

(43) Date of publication: 03.05.2006 Bulletin 2006/18 (21) Application number: 04743449.3 (22) Date of filing: 19.07.2004

(51) International Patent Classification (IPC):  C07D 401/12(1990.01) (86) International application number: PCT/GB2004/003111 (87) International publication number: WO 2005/014579 (17.02.2005 Gazette 2005/07)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 21.07.2003 SE 0302116 (71) Applicant: AstraZeneca AB 151 85 Södertälje (SE)	(72) Inventors: HUNT, Fraser, AstraZeneca R & D Charnwood Loughborough, Leicestershire LE11 5R (GB) HAMLEY, Peter, Aventis D-65926 Frankfurt (DE)