(19)

(11)

EP 1 651 635 A1

(12)

(43) Date of publication: 03.05.2006 Bulletin 2006/18 (21) Application number: 04744035.9 (22) Date of filing: 13.07.2004

(51) International Patent Classification (IPC):  C07D 401/12(1990.01) A61K 31/445(1985.01) A61K 31/44(1985.01) A61K 31/4427(2000.01) (86) International application number: PCT/IB2004/002376 (87) International publication number: WO 2005/009989 (03.02.2005 Gazette 2005/05)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 25.07.2003 GB 0317472 (71) Applicants: Pfizer Limited Sandwich, Kent CT13 9NJ (GB) GB  Pfizer Products Inc New York, NY 10017 (US) AT BE BG CH CY CZ DE DK EE ES FI FR GR HU IE IT LU MC NL PL	(72) Inventors: BAILEY, S., c/o Pfizer Global Res.& Development Sandwich, Kent CT13 9NJ (GB) BARBER, C.G., c/o Pfizer Global Res. & Development Sandwich, Kent CT13 9NJ (GB) (74) Representative: Laurent, Claire  Pfizer European Pharma Patent Department 23-25, avenue du Docteur Lannelongue 75668 Paris Cedex 14 75668 Paris Cedex 14 (FR)