(19)

(11)

EP 1 651 647 A1

(12)

(43) Date of publication: 03.05.2006 Bulletin 2006/18 (21) Application number: 04744024.3 (22) Date of filing: 13.07.2004

(51) International Patent Classification (IPC):  C07D 471/04(1985.01) A61K 31/455(1985.01) C07D 401/12(1990.01) A61P 37/00(2000.01) (86) International application number: PCT/IB2004/002365 (87) International publication number: WO 2005/010001 (03.02.2005 Gazette 2005/05)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR (30) Priority: 25.07.2003 GB 0317509 (71) Applicants: Pfizer Limited Sandwich, Kent CT13 9NJ (GB) GB  PFIZER INC. New York, N.Y. 10017 (US) AT BE BG CH CY CZ DE DK EE ES FI FR GR HU IE IT LU MC NL PL PT RO SE SI SK TR	(72) Inventor: MATHIAS, John Paul Sandwich, Kent CT13 9NJ (GB) (74) Representative: Laurent, Claire  Pfizer European Pharma Patent Department 23-25, avenue du Docteur Lannelongue 75668 Paris Cedex 14 75668 Paris Cedex 14 (FR)